ImageXpress Micro XL System
Now Turbocharged for 3X throughput!
Built on 25 years of cellular imaging experience, the new ImageXpress® Micro XL system lets you image three times as fast, delivering more statistically robust results for larger data sets in a third of the time. With the most comprehensive set of image analysis and data visualization tools available, the standard ImageXpress Micro and ImageXpress Micro XL systems set the standard for imaging flexibility. Explore how you can increase your lab's high-content screening speed without compromising quality.
ImageXpress Micro XL System
All the capabilities of the standard ImageXpress Micro system, plus these exciting enhancements:
- One well, one image
- Fewer images for large objects
- Statistically relevant results in half the time
- Instant-on, long-lived solid state light source
- Reliable assays with <5% CV of intensities across plate
Applications Performance
System Features
Analysis Software
Related Info
ImageXpress Micro Standard and XL Typical Performance
- High-resolution two-color Transfluor® beta arrestin translocation assay
- Medium resolution two-color large object neurotoxicity assay
- Low-resolution three-color cytotoxicity assay
Images of neurons obtained using iPSC-derived cells courtesy of Cellular Dynamics International, Inc.
The ImageXpress Micro Systems meet the challenges of the high-content screening environment where time-to-result and data quality are equally important.
Flexibility
- Highest image flexibility score (IFS) of any wide field high content screening system. Note: IFS = sensor size (4.66 megapixel) x magnifcation range (100) = 466
- Widest selection (> 25) of objectives
- 1x to 100x Objectives for a variety of magnification
- 0.05 to 0.95 numerical aperture (NA), air for variety in resolution and assay sensitivity
- Image small organisms through subcellular organelles
- Adjustable field-of-view focuses on sample area most appropriate for your assay
Extensive Sample Compatibility
- Slides
- 6 through 1536 well microplates
- Thick to thin well bottoms
- High and low profile microplates
Environmental Control for Live Cell Assays
- Live cell time course imaging, for hours or days
- Temperature, humidity and CO2 control
- Compatible with fluidics or transmitted light options
Molecular Devices offers the only true end-to-end solution for HCS, from acquisition through data analysis. To generate relevant numerical data from your high-content assays, Molecular Devices’ software works at every level, from extracting features from individual cells through multi-parametric analysis and visualization of multiple assays.
The Only End-to-End HCS Solution
- Digital confocal option to decrease exposure times >2X
- 19 turnkey application modules to address 100s of assays
- MetaXpress® PowerCore™ for high-throughput data analysis
- Only commercial system with AcuityXpress integrated analytics
- MDCStore Data Management
NEW! ImageXpress Micro Systems are now available with Digital Confocal Technology. The new Digital Confocal software option enhances contrast of images during acquisition, allowing you to decrease exposure time more than two fold and increase throughput while maintaining assay quality. Alternatively, assays with low Z' can be increased more than 25%.
Application Modules
Application Modules provide an interactive environment to determine features of interest based on size, intensities, and distances.
Interactive Setup and Review
NEW! Now launching MetaXpress 4.0 with 12 Application modules having a 2x faster object-finding algorithm option.
- Cell Cycle
- Cell Health
- Cell Scoring
- Count Nuclei
- Granularity
- Live Dead
- Mitotic Index
- Monopole Detection
- MWCS
- Transfluor
- Translocation
- Translocation Enhanced
All application modules provide an interactive environment to determine features of interest. 1: Optimize with interactive plots, histograms. 2: Measurements are displayed in a table on a cell-by-cell basis and can be used to optimize settings based on control images. 3: Settings saved within MDCStore™ Database can be used to reanalayze a set of wells or multiple plates. 4: Review and QC measurements.
MetaXpress PowerCore Software
NEW! MetaXpress® PowerCore™ Software is now compatible with the new fast algorithms of MetaXpress 4.0 Software.
A scalable parallel processing solution to drive application module analysis time to be faster than acquisition. MetaXpress PowerCore Software harnesses the power of parallel processing to allow HCS users to review data as soon as image acquisition is over. Image analysis for all application modules is sped up without compromising quality and is fully scalable, allowing HCS users to analyze screens ranging from a few plates to a million compounds.
Analysis becomes up to 25-fold faster than acquisition (384-well microplate, three images per well, 2MB per image) using four complex application modules.
